T2I (p.Thr2Ile) variant of IL7R (P16871)
T2I (p.Thr2Ile) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
T2I (p.Thr2Ile) variant details
- p.Thr2Ile
- gnomAD 5-35856982-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.33
- CADD 20.70
- PolyPhen-2 0.07
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available