S22I (p.Ser22Ile) variant of IL7R (P16871)
S22I (p.Ser22Ile) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
S22I (p.Ser22Ile) variant details
- p.Ser22Ile
- gnomAD 5-35857042-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.703
- REVEL 0.63
- CADD 27.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available