S19Y (p.Ser19Tyr) variant of IL7R (P16871)
S19Y (p.Ser19Tyr) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
S19Y (p.Ser19Tyr) variant details
- p.Ser19Tyr
- gnomAD rs1339277801
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.44
- CADD 24.20
- PolyPhen-2 0.99
- SIFT 0.06
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available