Q45R (p.Gln45Arg) variant of IL7R (P16871)
Q45R (p.Gln45Arg) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
Q45R (p.Gln45Arg) variant details
- p.Gln45Arg
- gnomAD 5-35860903-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.659
- REVEL 0.68
- CADD 25.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available