L4I (p.Leu4Ile) variant of IL7R (P16871)
L4I (p.Leu4Ile) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L4I (p.Leu4Ile) variant details
- p.Leu4Ile
- gnomAD 5-35856987-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.31
- CADD 23.60
- PolyPhen-2 0.94
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available