I3V (p.Ile3Val) variant of IL7R (P16871)
I3V (p.Ile3Val) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
I3V (p.Ile3Val) variant details
- p.Ile3Val
- gnomAD rs1193803606
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.16
- CADD 13.10
- PolyPhen-2 0.06
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available