G5S (p.Gly5Ser) variant of IL7R (P16871)
G5S (p.Gly5Ser) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G5S (p.Gly5Ser) variant details
- p.Gly5Ser
- gnomAD rs1374760636
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.09
- CADD 14.30
- PolyPhen-2 0.23
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available