G5D (p.Gly5Asp) variant of IL7R (P16871)
G5D (p.Gly5Asp) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G5D (p.Gly5Asp) variant details
- p.Gly5Asp
- cosmic curated COSV10514
- TOPMed rs1759658878
- gnomAD rs1759658878
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.36
- CADD 24.20
- PolyPhen-2 0.92
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available