G20A (p.Gly20Ala) variant of IL7R (P16871)
G20A (p.Gly20Ala) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
G20A (p.Gly20Ala) variant details
- p.Gly20Ala
- gnomAD 5-35857036-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- REVEL 0.58
- CADD 26.30
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available