A25V (p.Ala25Val) variant of IL7R (P16871)
A25V (p.Ala25Val) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
A25V (p.Ala25Val) variant details
- p.Ala25Val
- gnomAD 5-35857051-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.20
- CADD 22.70
- PolyPhen-2 0.44
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available