A25S (p.Ala25Ser) variant of IL7R (P16871)
A25S (p.Ala25Ser) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
A25S (p.Ala25Ser) variant details
- p.Ala25Ser
- Ensembl rs922409337
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.16
- CADD 23.50
- PolyPhen-2 0.47
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available