A25D (p.Ala25Asp) variant of IL7R (P16871)
A25D (p.Ala25Asp) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
A25D (p.Ala25Asp) variant details
- p.Ala25Asp
- gnomAD 5-35857051-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.36
- CADD 22.90
- PolyPhen-2 0.96
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available