V4L (p.Val4Leu) variant of IL6R (P08887)
V4L (p.Val4Leu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
V4L (p.Val4Leu) variant details
- p.Val4Leu
- gnomAD 1-154405639-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.02
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.25
- Population evidence available
- Structural context available
- Literature evidence available