T44S (p.Thr44Ser) variant of IL6R (P08887)
T44S (p.Thr44Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T44S (p.Thr44Ser) variant details
- p.Thr44Ser
- gnomAD rs1429634359
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.06
- CADD 8.19
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available