T36P (p.Thr36Pro) variant of IL6R (P08887)
T36P (p.Thr36Pro) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
T36P (p.Thr36Pro) variant details
- p.Thr36Pro
- gnomAD 1-154429216-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.19
- MetaLR 0.05
- MetaSVM -1.07
- CADD 16.00
- PolyPhen-2 0.52
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available