S42T (p.Ser42Thr) variant of IL6R (P08887)
S42T (p.Ser42Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
S42T (p.Ser42Thr) variant details
- p.Ser42Thr
- ExAC rs763907785
- TOPMed rs763907785
- gnomAD rs763907785
- Missense
- Variant Prioritization Score for Impact Estimate 0.0362
- REVEL 0.02
- CADD 0.10
- PolyPhen-2 0.00
- SIFT 0.37
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available