S37I (p.Ser37Ile) variant of IL6R (P08887)
S37I (p.Ser37Ile) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S37I (p.Ser37Ile) variant details
- p.Ser37Ile
- gnomAD 1-154429220-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.11
- MetaLR 0.06
- MetaSVM -1.09
- CADD 19.40
- PolyPhen-2 0.90
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available