S37G (p.Ser37Gly) variant of IL6R (P08887)
S37G (p.Ser37Gly) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S37G (p.Ser37Gly) variant details
- p.Ser37Gly
- TOPMed rs994608378
- gnomAD rs994608378
- Missense
- Variant Prioritization Score for Impact Estimate 0.0951
- REVEL 0.04
- CADD 7.48
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available