R24H (p.Arg24His) variant of IL6R (P08887)
R24H (p.Arg24His) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R24H (p.Arg24His) variant details
- p.Arg24His
- TOPMed rs1309026478
- Missense
- Variant Prioritization Score for Impact Estimate 0.0559
- REVEL 0.01
- CADD 8.37
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available