R24C (p.Arg24Cys) variant of IL6R (P08887)
R24C (p.Arg24Cys) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
R24C (p.Arg24Cys) variant details
- p.Arg24Cys
- gnomAD rs1398752017
- Missense
- Variant Prioritization Score for Impact Estimate 0.0892
- REVEL 0.04
- CADD 14.00
- PolyPhen-2 0.04
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available