R23M (p.Arg23Met) variant of IL6R (P08887)
R23M (p.Arg23Met) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
R23M (p.Arg23Met) variant details
- p.Arg23Met
- gnomAD 1-154405697-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0981
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.96
- CADD 12.70
- PolyPhen-2 0.03
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available