R23K (p.Arg23Lys) variant of IL6R (P08887)
R23K (p.Arg23Lys) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R23K (p.Arg23Lys) variant details
- p.Arg23Lys
- gnomAD rs1306195163
- Missense
- Variant Prioritization Score for Impact Estimate 0.0592
- REVEL 0.01
- CADD 5.79
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available