Q28L (p.Gln28Leu) variant of IL6R (P08887)
Q28L (p.Gln28Leu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
Q28L (p.Gln28Leu) variant details
- p.Gln28Leu
- gnomAD 1-154405712-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.09
- MetaLR 0.00
- MetaSVM -0.97
- CADD 7.49
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available