P39L (p.Pro39Leu) variant of IL6R (P08887)
P39L (p.Pro39Leu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
P39L (p.Pro39Leu) variant details
- p.Pro39Leu
- gnomAD 1-154429226-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.20
- MetaLR 0.04
- MetaSVM -1.05
- CADD 18.10
- PolyPhen-2 1.00
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available