P26R (p.Pro26Arg) variant of IL6R (P08887)
P26R (p.Pro26Arg) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
P26R (p.Pro26Arg) variant details
- p.Pro26Arg
- gnomAD 1-154405706-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.95
- CADD 10.80
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the REMAINING population (allele frequency 1.8e-05)
- Structural context available
- Literature evidence available