P22T (p.Pro22Thr) variant of IL6R (P08887)
P22T (p.Pro22Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
P22T (p.Pro22Thr) variant details
- p.Pro22Thr
- gnomAD 1-154405693-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.07
- MetaLR 0.01
- MetaSVM -1.00
- CADD 7.59
- PolyPhen-2 0.02
- SIFT 0.32
- Population evidence available
- Structural context available
- Literature evidence available