P16T (p.Pro16Thr) variant of IL6R (P08887)
P16T (p.Pro16Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
P16T (p.Pro16Thr) variant details
- p.Pro16Thr
- gnomAD 1-154405675-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.05
- MetaLR 0.01
- MetaSVM -0.96
- CADD 5.27
- PolyPhen-2 0.01
- SIFT 0.25
- Population evidence available
- Structural context available
- Literature evidence available