P16R (p.Pro16Arg) variant of IL6R (P08887)
P16R (p.Pro16Arg) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
P16R (p.Pro16Arg) variant details
- p.Pro16Arg
- gnomAD 1-154405676-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.05
- MetaLR 0.02
- MetaSVM -1.04
- CADD 8.58
- PolyPhen-2 0.25
- SIFT 0.33
- Population evidence available
- Structural context available
- Literature evidence available