L9Q (p.Leu9Gln) variant of IL6R (P08887)
L9Q (p.Leu9Gln) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L9Q (p.Leu9Gln) variant details
- p.Leu9Gln
- gnomAD 1-154405655-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.20
- MetaLR 0.10
- MetaSVM -1.05
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available