L9P (p.Leu9Pro) variant of IL6R (P08887)
L9P (p.Leu9Pro) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- gnomAD 1-154405655-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.30
- MetaLR 0.11
- MetaSVM -0.99
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available