L9M (p.Leu9Met) variant of IL6R (P08887)
L9M (p.Leu9Met) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L9M (p.Leu9Met) variant details
- p.Leu9Met
- gnomAD 1-154405654-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.16
- MetaLR 0.08
- MetaSVM -1.08
- CADD 21.90
- PolyPhen-2 1.00
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available