L35Q (p.Leu35Gln) variant of IL6R (P08887)
L35Q (p.Leu35Gln) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L35Q (p.Leu35Gln) variant details
- p.Leu35Gln
- ExAC rs773458420
- TOPMed rs773458420
- gnomAD rs773458420
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.12
- CADD 17.00
- PolyPhen-2 0.04
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 0.00019)
- Structural context available