L35P (p.Leu35Pro) variant of IL6R (P08887)
L35P (p.Leu35Pro) in IL6R (P08887) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
L35P (p.Leu35Pro) variant details
- p.Leu35Pro
- gnomAD 1-154429211-TGCTG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.574
- CADD 23.50
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available