L2P (p.Leu2Pro) variant of IL6R (P08887)
L2P (p.Leu2Pro) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L2P (p.Leu2Pro) variant details
- p.Leu2Pro
- gnomAD 1-154405634-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.14
- CADD 26.60
- PolyPhen-2 0.96
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available