L13P (p.Leu13Pro) variant of IL6R (P08887)
L13P (p.Leu13Pro) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L13P (p.Leu13Pro) variant details
- p.Leu13Pro
- gnomAD 1-154405667-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.23
- MetaLR 0.08
- MetaSVM -1.02
- CADD 22.90
- PolyPhen-2 0.96
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available