L13M (p.Leu13Met) variant of IL6R (P08887)
L13M (p.Leu13Met) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L13M (p.Leu13Met) variant details
- p.Leu13Met
- gnomAD 1-154405666-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.10
- CADD 20.50
- PolyPhen-2 0.94
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available