G5S (p.Gly5Ser) variant of IL6R (P08887)
G5S (p.Gly5Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
G5S (p.Gly5Ser) variant details
- p.Gly5Ser
- gnomAD 1-154405642-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.12
- CADD 5.13
- PolyPhen-2 0.04
- SIFT 0.77
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available