G5R (p.Gly5Arg) variant of IL6R (P08887)
G5R (p.Gly5Arg) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G5R (p.Gly5Arg) variant details
- p.Gly5Arg
- TOPMed rs1315405835
- gnomAD rs1315405835
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.22
- CADD 5.03
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available