G5D (p.Gly5Asp) variant of IL6R (P08887)
G5D (p.Gly5Asp) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
G5D (p.Gly5Asp) variant details
- p.Gly5Asp
- gnomAD 1-154405643-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.20
- CADD 12.90
- PolyPhen-2 0.07
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available