G40V (p.Gly40Val) variant of IL6R (P08887)
G40V (p.Gly40Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G40V (p.Gly40Val) variant details
- p.Gly40Val
- TOPMed rs1165971497
- gnomAD rs1165971497
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.41
- CADD 24.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available