G17V (p.Gly17Val) variant of IL6R (P08887)
G17V (p.Gly17Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
G17V (p.Gly17Val) variant details
- p.Gly17Val
- gnomAD 1-154405679-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.06
- MetaLR 0.02
- MetaSVM -1.03
- CADD 17.20
- PolyPhen-2 0.20
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available