G17R (p.Gly17Arg) variant of IL6R (P08887)
G17R (p.Gly17Arg) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- gnomAD rs1253366021
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.06
- CADD 18.90
- PolyPhen-2 0.42
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available