G17E (p.Gly17Glu) variant of IL6R (P08887)
G17E (p.Gly17Glu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
G17E (p.Gly17Glu) variant details
- p.Gly17Glu
- gnomAD 1-154405679-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -1.00
- CADD 15.90
- PolyPhen-2 0.03
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available