C6S (p.Cys6Ser) variant of IL6R (P08887)
C6S (p.Cys6Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
C6S (p.Cys6Ser) variant details
- p.Cys6Ser
- gnomAD 1-154405645-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.19
- CADD 16.30
- PolyPhen-2 0.42
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available