C6R (p.Cys6Arg) variant of IL6R (P08887)
C6R (p.Cys6Arg) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
C6R (p.Cys6Arg) variant details
- p.Cys6Arg
- gnomAD 1-154405645-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.12
- CADD 20.40
- PolyPhen-2 0.01
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available