C6F (p.Cys6Phe) variant of IL6R (P08887)
C6F (p.Cys6Phe) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
C6F (p.Cys6Phe) variant details
- p.Cys6Phe
- gnomAD 1-154405646-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.25
- CADD 23.40
- PolyPhen-2 0.75
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available