C25* (p.Cys25Ter) variant of IL6R (P08887)
C25* (p.Cys25Ter) in IL6R (P08887) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
C25* (p.Cys25Ter) variant details
- p.Cys25Ter
- TOPMed rs1287550693
- gnomAD rs1287550693
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.84
- CADD 32.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available