A7S (p.Ala7Ser) variant of IL6R (P08887)
A7S (p.Ala7Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A7S (p.Ala7Ser) variant details
- p.Ala7Ser
- gnomAD 1-154405648-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.09
- CADD 16.40
- PolyPhen-2 0.46
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available