A31A (p.Ala31Ala) variant of IL6R (P08887)
A31A (p.Ala31Ala) in IL6R (P08887) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
A31A (p.Ala31Ala) variant details
- p.Ala31Ala
- rs2228144
- gnomAD 1-154429203-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0862
- CADD 0.78
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 0.36)
- Structural context available
- Cited in: Genetic overlap and causality between COVID-19 and multi-site chronic pain: the importance of immunity. (PMID 38633255)
- Cited in: Abstracts from the 54(th) European Society of Human Genetics (ESHG) Conference: e-Posters. (PMID 35393538)