A27V (p.Ala27Val) variant of IL6R (P08887)
A27V (p.Ala27Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
A27V (p.Ala27Val) variant details
- p.Ala27Val
- gnomAD 1-154405709-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.01
- MetaLR 0.01
- MetaSVM -0.93
- CADD 9.01
- PolyPhen-2 0.00
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available